In healthcare facilities, the risk of more serious staph infection is higher because many patients have weakened immune systems or have undergone procedures. In healthcare, the risk of more serious staph infection is higher for patients in intensive care units ICUs , patients who have undergone certain types of surgeries and patients with medical devices inserted in their bodies. Skip directly to site content Skip directly to page options Skip directly to A-Z link. Section Navigation. Facebook Twitter LinkedIn Syndicate.
Batra, R. Throat and rectal swabs may have an important role in MRSA screening of critically ill patients. Intensive Care Med. Gagnaire, J. Epidemiology and clinical relevance of Staphylococcus aureus intestinal carriage: a systematic review and meta-analysis. Expert Rev. Anti Infect. Mermel, L. Methicillin-resistant Staphylococcus aureus colonization at different body sites: a prospective, quantitative analysis.
Lauderdale, T. Carriage rates of methicillin-resistant Staphylococcus aureus MRSA depend on anatomic location, the number of sites cultured, culture methods, and the distribution of clonotypes. McKinnell, J. Quantifying the impact of extranasal testing of body sites for methicillin-resistant Staphylococcus aureus colonization at the time of hospital or intensive care unit admission.
Anatomic sites of colonization with community-associated methicillin-resistant Staphylococcus aureus. Vos, M. Bartels, M. Rise and subsequent decline of community-associated methicillin resistant Staphylococcus aureus STIVc in Copenhagen, Denmark through an effective search and destroy policy.
Jain, R. Veterans Affairs initiative to prevent methicillin-resistant Staphylococcus aureus infections. This study demonstrates that the implementation of a MRSA bundle that couples active surveillance with contact precautions and hand hygiene results in decreased rates of health-care-associated MRSA infections.
Robicsek, A. Topical therapy for methicillin-resistant Staphylococcus aureus colonization: impact on infection risk. Harbarth, S. Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients. Saraswat, M. Preoperative Staphylococcus aureus screening and targeted decolonization in cardiac surgery. Jog, S. Impact of preoperative screening for meticillin-resistant Staphylococcus aureus by real-time polymerase chain reaction in patients undergoing cardiac surgery.
Targeted versus universal decolonization to prevent ICU infection. This large multicentre study shows that universal decolonization is more effective than targeted decolonization or screening and isolation in reducing rates of MRSA clinical isolates and bloodstream infection in patients in the ICU.
Climo, M. Effect of daily chlorhexidine bathing on hospital-acquired infection. This study shows that daily bathing with chlorhexidine reduces the risks of acquisition of multidrug-resistant organisms and hospital-acquired bloodstream infections. Lindgren, A. Eradication of methicillin-resistant Staphylococcus aureus MRSA throat carriage: a randomised trial comparing topical treatment with rifampicin-based systemic therapy.
Agents 51 , — Kaasch, A. Use of a simple criteria set for guiding echocardiography in nosocomial Staphylococcus aureus bacteremia. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: Update by the Infectious Diseases Society of America. Neely, M. Are vancomycin trough concentrations adequate for optimal dosing?
The clinical significance of vancomycin minimum inhibitory concentration in Staphylococcus aureus infections: a systematic review and meta-analysis. Fowler, V. Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus. This is one of very few RCTs addressing the treatment of MRSA bacteraemia or endocarditis, proving daptomycin is non-inferior to vancomycin.
Silverman, J. Inhibition of daptomycin by pulmonary surfactant: in vitro modeling and clinical impact. Sharma, M. High rate of decreasing daptomycin susceptibility during the treatment of persistent Staphylococcus aureus bacteremia. Gasch, O. Emergence of resistance to daptomycin in a cohort of patients with methicillin-resistant Staphylococcus aureus persistent bacteraemia treated with daptomycin.
Stryjewski, M. Raad, I. Efficacy and safety of weekly dalbavancin therapy for catheter-related bloodstream infection caused by gram-positive pathogens. Wilcox, M. Complicated skin and skin-structure infections and catheter-related bloodstream infections: noninferiority of linezolid in a phase 3 study. Casapao, A. Large retrospective evaluation of the effectiveness and safety of ceftaroline fosamil therapy. Davis, J. Combination of vancomycin and beta-lactam therapy for methicillin-resistant Staphylococcus aureus bacteremia: a pilot multicenter randomized controlled trial.
US National Library of Medicine. Thwaites, G. Adjunctive rifampicin for Staphylococcus aureus bacteraemia ARREST : a multicentre, randomised, double-blind, placebo-controlled trial. Cosgrove, S. Clinical Infectious Diseases ; Rehm, S. Daptomycin versus vancomycin plus gentamicin for treatment of bacteraemia and endocarditis due to Staphylococcus aureus : subset analysis of patients infected with methicillin-resistant isolates. Liu, C. Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children.
Holland, T. Effect of algorithm-based therapy versus usual care on clinical success and serious adverse events in patients with staphylococcal bacteremia: a randomized clinical trial.
Tissot, F. Mandatory infectious diseases consultation for MRSA bacteremia is associated with reduced mortality. Jenkins, T. Impact of routine infectious diseases service consultation on the evaluation, management, and outcomes of Staphylococcus aureus bacteremia.
Baddour, L. Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications: a scientific statement for healthcare professionals from the American Heart Association. Circulation , — Kang, D.
Early surgery versus conventional treatment for infective endocarditis. Martinez-Aguilar, G. Clindamycin treatment of invasive infections caused by community-acquired, methicillin-resistant and methicillin-susceptible Staphylococcus aureus in children.
Wunderink, R. Linezolid in methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study. Conte, J. Intrapulmonary pharmacokinetics of linezolid. Kalil, A. Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: a systematic review and meta-analysis.
Care Med. Dombrowski, J. Clinical failures of appropriately-treated methicillin-resistant Staphylococcus aureus infections. Moenster, R. Daptomycin compared to vancomycin for the treatment of osteomyelitis: a single-center, retrospective cohort study.
Gallagher, J. Daptomycin therapy for osteomyelitis: a retrospective study. Seaton, R. Senneville, E. Effectiveness and tolerability of prolonged linezolid treatment for chronic osteomyelitis: a retrospective study. Feigin, R. Clindamycin treatment of osteomyelitis and septic arthritis in children. Pediatrics 55 , — Daver, N. Oral step-down therapy is comparable to intravenous therapy for Staphylococcus aureus osteomyelitis. Park, K. Optimal duration of antibiotic therapy in patients with hematogenous vertebral osteomyelitis at low risk and high risk of recurrence.
Bejon, P. Two-stage revision for prosthetic joint infection: predictors of outcome and the role of reimplantation microbiology.
Zimmerli, W. Prosthetic-joint infections. Lora-Tamayo, J. A large multicenter study of methicillin-susceptible and methicillin-resistant Staphylococcus aureus prosthetic joint infections managed with implant retention. Westberg, M. Early prosthetic joint infections treated with debridement and implant retention: 38 primary hip arthroplasties prospectively recorded and followed for median 4 years. Acta Orthop. Daum, R. A placebo-controlled trial of antibiotics for smaller skin abscesses.
This is one of the most recent studies to address the need for antibiotics following incision and drainage of a cutaneous abscess. This study finds a reduced risk of recurrence for those receiving oral antibiotics following abscess drainage. A phase 3, randomized, double-blind, multicenter study to evaluate the safety and efficacy of intravenous iclaprim versus vancomycin for treatment of acute bacterial skin and skin structure infections suspected or confirmed to be due to Gram-positive pathogens REVIVE-2 study.
A phase 3, randomized, double-blind, multicenter study to evaluate the safety and efficacy of intravenous iclaprim vs vancomycin for the treatment of acute bacterial skin and skin structure infections suspected or confirmed to be due to Gram-positive pathogens: REVIVE Single-dose oritavancin in the treatment of acute bacterial skin infections. Once-weekly dalbavancin versus daily conventional therapy for skin infection.
Dunne, M. A randomized clinical trial of single-dose versus weekly dalbavancin for treatment of acute bacterial skin and skin structure infection. Shinefield, H. Use of a conjugate vaccine in patients receiving hemodialysis. Giersing, B. Status of vaccine research and development of vaccines for Staphylococcus aureus.
Vaccine 34 , — Rutherford, K. Artemis: sequence visualization and annotation. Bioinformatics 16 , — Omuse, G. Molecular characterization of Staphylococcus aureus isolates from various healthcare institutions in Nairobi, Kenya: a cross sectional study. Xiao, M.
National surveillance of methicillin-resistant Staphylococcus aureus in China highlights a still-evolving epidemiology with 15 novel emerging multilocus sequence types. Kang, G. Prevalence of major methicillin-resistant Staphylococcus aureus clones in Korea between and Gostev, V.
Molecular epidemiology and antibiotic resistance of methicillin-resistant Staphylococcus aureus circulating in the Russian Federation. Drougka, E. Udo, E. Comparing pulsed-field gel electrophoresis with multilocus sequence typing, spa typing, staphylococcal cassette chromosome mec SCCmec typing, and PCR for Panton-Valentine leukocidin, arcA, and opp3 in methicillin-resistant Staphylococcus aureus isolates at a US Medical Center.
Diekema, D. Continued emergence of USA methicillin-reistant Staphylococcus aureus in the United States: results from a nationwide surveillance study. Nichol, K. Changing epidemiology of methicillin-resistant Staphylococcus aureus in Canada.
Sharma-Kuinkel, B. Potential influence of Staphylococcus aureus clonal complex 30 genotype and transcriptome on hematogenous infections. Open Forum Infect. Kuroda, M. Whole genome sequencing of meticillin-resistant Staphylococcus aureus.
Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Pulse field gel electrophoresis. Methods Mol. Poor value of pulsed-field gel electrophoresis to investigate long-term scale epidemiology of methicillin-resistant Staphylococcus aureus. Enright, M. Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus. Drug Resist. Mathema, B.
Sequence analysis of the variable number tandem repeat in Staphylococcus aureus protein A gene: spa typing. Brandt, K. Evaluation of multiple-locus variable number of tandem repeats analysis for typing livestock-associated methicillin-resistant Staphylococcus aureus.
Garcia-Alvarez, L. Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study. Ross, T. Comparison of an automated repetitive sequence-based PCR microbial typing system to pulsed-field gel electrophoresis for analysis of outbreaks of methicillin-resistant Staphylococcus aureus. Salipante, S. Application of whole-genome sequencing for bacterial strain typing in molecular epidemiology.
Cramton, S. Identification of a new repetitive element in Staphylococcus aureus. Quelle, L. STAR gene restriction profile analysis in epidemiological typing of methicillin-resistant Staphylococcus aureus : description of the new method and comparison with other polymerase chain reaction PCR -based methods. The effect of daily bathing with chlorhexidine on the acquisition of methicillin-resistant Staphylococcus aureus , vancomycin-resistant Enterococcus , and healthcare-associated bloodstream infections: results of a quasi-experimental multicenter trial.
Universal surveillance for methicillin-resistant Staphylococcus aureus in 3 affiliated hospitals. Dillon, H. Clinical experience with clindamycin hydrochloride: I. Treatment of streptococcal and mixed streptococcal-staphylococcal skin infections. Nissen, R. Skov, J. Knudsen, C. Ostergaard, H. Effectiveness of penicillin, dicloxacillin and cefuroxime for penicillin-susceptible Staphylococcus aureus bacteraemia: a retrospective, propensity-score-adjusted case-control and cohort analysis.
J Antimicrob Chemother. Henderson, P. Harris, G. Hartel, D. Paterson, J. Turnidge, J. Davis, et al. Benzylpenicillin versus flucloxacillin for penicillin susceptible Staphylococcus aureus bloodstream infections from a large retrospective cohort study. Int J of Antimicrob Agents.
Cheng, P. Cheng, T. Back to the Future: Penicillin-Susceptible Staphylococcus aureus. Am J Med. Hagstrand Aldman, A. Skovby, L. Penicillin-susceptible Staphylococcus aureus : susceptibility testing, resistance rates and outcome of infection. Infect Dis Lond. Chabot, M. Stefan, J. Friderici, J.
Schimmel, J. Reappearance and treatment of penicillin-susceptible Staphylococcus aureus in a tertiary medical centre. Butler-Laporte, T. Lee, M. Increasing Rates of Penicillin Sensitivity in Staphylococcus aureus. Antimicrob Agents Chemother.
Koeck, K. Como-Sabetti, D. Boxrud, G. Dobbins, A. Glennen, et al. Burdens of invasive methicillin-susceptible and methicillin-resistant Staphylococcus aureus disease, Minnesota, USA. Emerg Infect Dis. Richter, G. Doern, K. Heilmann, S. Register for free on Medscape to access. Nearly 1 in 10 serious staph infections in occurred in people who inject drugs such as opioids.
Staph can cause serious infections if it gets into the blood and can lead to sepsis or death. Skip directly to site content Skip directly to page options Skip directly to A-Z link. Vital Signs. Section Navigation. Facebook Twitter LinkedIn Syndicate. Staph infections can kill. Minus Related Pages. More than , bloodstream staph infections occurred in
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